Germline Modification and Engineering in Avian Species
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چکیده
منابع مشابه
Germline Modification and Engineering in Avian Species
Production of genome-edited animals using germline-competent cells and genetic modification tools has provided opportunities for investigation of biological mechanisms in various organisms. The recently reported programmed genome editing technology that can induce gene modification at a target locus in an efficient and precise manner facilitates establishment of animal models. In this regard, t...
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Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent stem cells have contributed to the generation of avian model systems and the conservation of avian...
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The rapid development of genome modification technology has provided many great benefits in diverse areas of research and industry. Genome modification technologies have also been actively used in a variety of research areas and fields of industry in avian species. Transgenic technologies such as lentiviral systems and piggyBac transposition have been used to produce transgenic birds for divers...
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A framework for open discourse on the use of CRISPR-Cas9 technology to manipulate the human genome is urgently needed Correspondence to: Jennifer A. Doudna, [email protected]. HHS Public Access Author manuscript Science. Author manuscript; available in PMC 2015 October 03. Published in final edited form as: Science. 2015 April 3; 348(6230): 36–38. doi:10.1126/science.aab1028. A uhor M anscript
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ژورنال
عنوان ژورنال: Molecules and Cells
سال: 2015
ISSN: 1016-8478,0219-1032
DOI: 10.14348/molcells.2015.0225